Life Science

Life science has a direct connection in improving the quality of life for all of humanity. Advances in this domain have innumerable applications in the health, pharamaceutical, and agricultural industries. As time marches on, we are pressed by new challenges to better understand the phenomena of life not yet illuminated by the light of science. One such daunting frontier is at the nanoscale. Applying atomic force microscopy (AFM) to life science, researchers are now allowed to begin exploring the darkened mysteries at this border with the unknown.

Researchers using Park AFM in life science can acquire the nanoscale morphology of biological samples accurately and easily. Of particular use is the the force-distance spectroscopy that AFM provides. This technique allows for the characterization of biological materials along such physical properties as stiffness, adhesion, and even its Young's modulus with sub-nN level precision.

Furthermore, Park AFM has developed an innovative in-liquid imaging technology, Scanning Ion Conductance Microscopy (SICM). This technique has enabled researchers to study complicated physiological phenomena in liquid directly, something not possible with conventional microscopes. Not only are physiological biomaterials and live cells able to be imaged with Park SICM, but various pipette-based applications can be integrated into the investigation such as patch clamping for ion channel signal detection, electrochemical reaction analyses, and even nanoinjections or nanobiopsies.